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DeCS
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Descriptor English:
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Nod Signaling Adaptor Proteins
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Descriptor Spanish:
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Proteínas Adaptadoras de Señalización NOD
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Descriptor Portuguese:
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Proteínas Adaptadoras de Sinalização NOD
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Synonyms English:
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Nuclear-Binding Oligomerization Domain Proteins
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Tree Number:
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D12.644.360.024.307
D12.776.157.057.068
D12.776.476.024.391
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Definition English:
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Cytosolic signaling adaptor proteins that were initially discovered by their role in the innate immunity (IMMUNITY, INNATE) response of organisms that lack an adaptive immune system. This class of proteins contains three domains, a C-terminal ligand recognition domain, an N-terminal effector-binding domain, and a centrally located nuclear-binding oligomerization domain. Many members of this class contain a C-terminal leucine rich domain which binds to PEPTIDOGLYCAN on the surface of BACTERIA and plays a role in pathogen resistance. |
History Note English:
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2007
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Allowable Qualifiers English:
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Record Number:
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52314
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Unique Identifier:
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D053472
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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